ESTPiper – a web-based analysis pipeline for expressed sequence tags
نویسندگان
چکیده
منابع مشابه
Creating a Workflow for Expressed Sequence Tags Analysis
Expressed sequence tags (ESTs) are short sequence fragments of genes and may be used in genomic and genetic investigations. Despite rapid expansion of EST generation process, the resulting sequences are relatively low quality fragments and need to be cleaned before assembling into a larger sequence by identifying overlaps between sample sequences. EST comparative analysis and functional assignm...
متن کاملExpressed sequence tags: analysis and annotation.
Expressed sequence tags (ESTs) present a special set of problems for bioinformatic analysis. They are partial and error-prone, and large datasets can have significant internal redundancy. To facilitate analysis of small EST datasets from in-house projects, we present an integrated "pipeline" of tools that take EST data from sequence trace to database submission. These tools also can be used to ...
متن کاملExpressed Sequence Tags
Now a days, genome analysis has employed a rapid analysis tool known as expressed sequence tags. In 1983, SD Putney for the first time demonstrated the use of cDNA in identification of genome. The term expressed sequence tags (ESTs) was coined by Anthony Kerlavage at the Institute for Genomic Research. In 1991, Mark Adams used EST in relation to gene discovery and Human Genome project. cDNA or ...
متن کاملP-215: Discovery of A Novel APA Variant of A Human Potential Gene Based on Expressed Sequenced Tags Analysis
Background: Expressed sequence tags (ESTs) are sequences of cDNA fragments prepared from different tissue sources. There are over one million of these sequences in the publicly available database, and these sequences are believed to represent more than half of all human genes. The ESTs belong to different cDNA libraries, was prepared from one particular cell type, organ, or tumor. Therefore, th...
متن کاملAlgorithms for the Analysis of Expressed Sequence Tags
A problem in EST clustering is the presence of repeat sequences. To avoid false matches, repeats have to be masked. This can be a time consuming process, and it depends on available repeat libraries. We present a fast and library independent method to eliminate this problem in the process of clustering. We demonstrate that the result is very similar to performing standard repeat masking before ...
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ژورنال
عنوان ژورنال: BMC Genomics
سال: 2009
ISSN: 1471-2164
DOI: 10.1186/1471-2164-10-174